No brain structure abnormalities in boys with Tourette's syndrome: A voxel‐based morphometry study
Identifieur interne : 002180 ( Main/Exploration ); précédent : 002179; suivant : 002181No brain structure abnormalities in boys with Tourette's syndrome: A voxel‐based morphometry study
Auteurs : Veit Roessner [Allemagne] ; Sebastian Overlack [Allemagne] ; Juergen Baudewig [Allemagne] ; Peter Dechent [Allemagne] ; Aribert Rothenberger [Allemagne] ; Gunther Helms [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-12-15.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Enfant, Neurologie, Psychiatrie.
English descriptors
- KwdEn :
- Adolescent, Analysis of Variance, Brain (pathology), Brain Mapping, Child, Encephalon, Gilles de la Tourette syndrome, Humans, Image Processing, Computer-Assisted, MRI, Magnetic Resonance Imaging (methods), Male, Morphometry, Nervous system diseases, Neurology, Nuclear magnetic resonance imaging, Psychiatry, Tic, Tourette Syndrome (pathology), Voxel, child neurology, child psychiatry, tics.
- MESH :
- methods : Magnetic Resonance Imaging.
- pathology : Brain, Tourette Syndrome.
- Adolescent, Analysis of Variance, Brain Mapping, Child, Humans, Image Processing, Computer-Assisted, Male.
Abstract
Morphometric findings in Tourette's syndrome (TS) are still inconsistent probably due to differences in analysis approaches as well as several confounders (coexisting psychiatric conditions, medication status, etc.). Our aim was to identify possible morphometric changes in a well‐defined sample of drug‐naïve boys with “pure” TS. High‐resolution structural magnetic resonance images of 38 boys with TS were compared with those of 38 healthy boys matched for age and IQ using voxel‐based morphometry (VBM). Coexisting psychiatric conditions and previous medication were excluded. The inclusion of 10‐ to 15‐year‐old boys minimized the well known compensatory changes due to tic suppression over many years. VBM analyses revealed no differences between the treatment naïve boys with “pure” TS and healthy controls. Brain morphology is not altered in boys with “pure” TS. Further studies should reveal whether previous findings might be ascribed to confounding factors like coexisting psychiatric conditions or long‐term compensatory mechanisms due to voluntary tic suppression. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22847
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001F03
- to stream Istex, to step Curation: 001F03
- to stream Istex, to step Checkpoint: 000D82
- to stream PubMed, to step Corpus: 001B01
- to stream PubMed, to step Curation: 001B01
- to stream PubMed, to step Checkpoint: 001C87
- to stream Ncbi, to step Merge: 002882
- to stream Ncbi, to step Curation: 002882
- to stream Ncbi, to step Checkpoint: 002882
- to stream Main, to step Merge: 002A41
- to stream PascalFrancis, to step Corpus: 000C57
- to stream PascalFrancis, to step Curation: 002062
- to stream PascalFrancis, to step Checkpoint: 000D85
- to stream Main, to step Merge: 002E82
- to stream Main, to step Curation: 002180
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">No brain structure abnormalities in boys with Tourette's syndrome: A voxel‐based morphometry study</title><author><name sortKey="Roessner, Veit" sort="Roessner, Veit" uniqKey="Roessner V" first="Veit" last="Roessner">Veit Roessner</name></author><author><name sortKey="Overlack, Sebastian" sort="Overlack, Sebastian" uniqKey="Overlack S" first="Sebastian" last="Overlack">Sebastian Overlack</name></author><author><name sortKey="Baudewig, Juergen" sort="Baudewig, Juergen" uniqKey="Baudewig J" first="Juergen" last="Baudewig">Juergen Baudewig</name></author><author><name sortKey="Dechent, Peter" sort="Dechent, Peter" uniqKey="Dechent P" first="Peter" last="Dechent">Peter Dechent</name></author><author><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name></author><author><name sortKey="Helms, Gunther" sort="Helms, Gunther" uniqKey="Helms G" first="Gunther" last="Helms">Gunther Helms</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F888CE5F133A7BB5E6F0E631D30E504D82A80BC2</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22847</idno><idno type="url">https://api.istex.fr/document/F888CE5F133A7BB5E6F0E631D30E504D82A80BC2/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001F03</idno><idno type="wicri:Area/Istex/Curation">001F03</idno><idno type="wicri:Area/Istex/Checkpoint">000D82</idno><idno type="wicri:doubleKey">0885-3185:2009:Roessner V:no:brain:structure</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:19890999</idno><idno type="wicri:Area/PubMed/Corpus">001B01</idno><idno type="wicri:Area/PubMed/Curation">001B01</idno><idno type="wicri:Area/PubMed/Checkpoint">001C87</idno><idno type="wicri:Area/Ncbi/Merge">002882</idno><idno type="wicri:Area/Ncbi/Curation">002882</idno><idno type="wicri:Area/Ncbi/Checkpoint">002882</idno><idno type="wicri:Area/Main/Merge">002A41</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:10-0071270</idno><idno type="wicri:Area/PascalFrancis/Corpus">000C57</idno><idno type="wicri:Area/PascalFrancis/Curation">002062</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000D85</idno><idno type="wicri:doubleKey">0885-3185:2009:Roessner V:no:brain:structure</idno><idno type="wicri:Area/Main/Merge">002E82</idno><idno type="wicri:Area/Main/Curation">002180</idno><idno type="wicri:Area/Main/Exploration">002180</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">No brain structure abnormalities in boys with Tourette's syndrome: A voxel‐based morphometry study</title><author><name sortKey="Roessner, Veit" sort="Roessner, Veit" uniqKey="Roessner V" first="Veit" last="Roessner">Veit Roessner</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Overlack, Sebastian" sort="Overlack, Sebastian" uniqKey="Overlack S" first="Sebastian" last="Overlack">Sebastian Overlack</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Baudewig, Juergen" sort="Baudewig, Juergen" uniqKey="Baudewig J" first="Juergen" last="Baudewig">Juergen Baudewig</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>MR‐Research in Neurology and Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Dechent, Peter" sort="Dechent, Peter" uniqKey="Dechent P" first="Peter" last="Dechent">Peter Dechent</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>MR‐Research in Neurology and Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author><author><name sortKey="Helms, Gunther" sort="Helms, Gunther" uniqKey="Helms G" first="Gunther" last="Helms">Gunther Helms</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>MR‐Research in Neurology and Psychiatry, University Medical Center, Goettingen</wicri:regionArea><wicri:noRegion>Goettingen</wicri:noRegion><wicri:noRegion>Goettingen</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-12-15">2009-12-15</date><biblScope unit="vol">24</biblScope><biblScope unit="issue">16</biblScope><biblScope unit="page" from="2398">2398</biblScope><biblScope unit="page" to="2403">2403</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">F888CE5F133A7BB5E6F0E631D30E504D82A80BC2</idno><idno type="DOI">10.1002/mds.22847</idno><idno type="ArticleID">MDS22847</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Analysis of Variance</term><term>Brain (pathology)</term><term>Brain Mapping</term><term>Child</term><term>Encephalon</term><term>Gilles de la Tourette syndrome</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>MRI</term><term>Magnetic Resonance Imaging (methods)</term><term>Male</term><term>Morphometry</term><term>Nervous system diseases</term><term>Neurology</term><term>Nuclear magnetic resonance imaging</term><term>Psychiatry</term><term>Tic</term><term>Tourette Syndrome (pathology)</term><term>Voxel</term><term>child neurology</term><term>child psychiatry</term><term>tics</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Magnetic Resonance Imaging</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Tourette Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Analysis of Variance</term><term>Brain Mapping</term><term>Child</term><term>Humans</term><term>Image Processing, Computer-Assisted</term><term>Male</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Encéphale</term><term>Enfant</term><term>Imagerie RMN</term><term>Morphométrie</term><term>Neurologie</term><term>Pathologie du système nerveux</term><term>Psychiatrie</term><term>Syndrome de Gilles de la Tourette</term><term>Tic</term><term>Voxel</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Enfant</term><term>Neurologie</term><term>Psychiatrie</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Morphometric findings in Tourette's syndrome (TS) are still inconsistent probably due to differences in analysis approaches as well as several confounders (coexisting psychiatric conditions, medication status, etc.). Our aim was to identify possible morphometric changes in a well‐defined sample of drug‐naïve boys with “pure” TS. High‐resolution structural magnetic resonance images of 38 boys with TS were compared with those of 38 healthy boys matched for age and IQ using voxel‐based morphometry (VBM). Coexisting psychiatric conditions and previous medication were excluded. The inclusion of 10‐ to 15‐year‐old boys minimized the well known compensatory changes due to tic suppression over many years. VBM analyses revealed no differences between the treatment naïve boys with “pure” TS and healthy controls. Brain morphology is not altered in boys with “pure” TS. Further studies should reveal whether previous findings might be ascribed to confounding factors like coexisting psychiatric conditions or long‐term compensatory mechanisms due to voluntary tic suppression. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>District de Dresde</li><li>Saxe (Land)</li></region><settlement><li>Dresde</li></settlement></list><tree><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Roessner, Veit" sort="Roessner, Veit" uniqKey="Roessner V" first="Veit" last="Roessner">Veit Roessner</name></region><name sortKey="Baudewig, Juergen" sort="Baudewig, Juergen" uniqKey="Baudewig J" first="Juergen" last="Baudewig">Juergen Baudewig</name><name sortKey="Dechent, Peter" sort="Dechent, Peter" uniqKey="Dechent P" first="Peter" last="Dechent">Peter Dechent</name><name sortKey="Helms, Gunther" sort="Helms, Gunther" uniqKey="Helms G" first="Gunther" last="Helms">Gunther Helms</name><name sortKey="Overlack, Sebastian" sort="Overlack, Sebastian" uniqKey="Overlack S" first="Sebastian" last="Overlack">Sebastian Overlack</name><name sortKey="Roessner, Veit" sort="Roessner, Veit" uniqKey="Roessner V" first="Veit" last="Roessner">Veit Roessner</name><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002180 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002180 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:F888CE5F133A7BB5E6F0E631D30E504D82A80BC2
|texte= No brain structure abnormalities in boys with Tourette's syndrome: A voxel‐based morphometry study
}}
| This area was generated with Dilib version V0.6.23. |  |